Topic 2.4: proteins
In the Basics of Biochemistry unit students are introduced to the major classes of biologically important molecules and the types of reactions used to build and break apart those molecules. The structure and function of water, as the medium of life, is also a focus. The unit is planned to take 8 school days.
Nature of science:
- Looking for patterns, trends and discrepancies—most but not all organisms assemble proteins from the same amino acids. (3.1)
- Proteins have a very wide range of functions in living organisms.
2.4.U.1 Amino acids are linked together by condensation to form polypeptides.
2.4.U.2 There are 20 different amino acids in polypeptides synthesized on ribosomes.
2.4.U.3 Amino acids can be linked together in any sequence giving a huge range of
2.4.U.4 The amino acid sequence of polypeptides is coded for by genes.
2.4.U.5 A protein may consist of a single polypeptide or more than one polypeptide linked together.
2.4.U.6 The amino acid sequence determines the three-dimensional conformation of a protein.
2.4.U.7 Living organisms synthesize many different proteins with a wide range of functions.
2.4.U.8 Every individual has a unique proteome.
2.4.A.1Rubisco, insulin, immunoglobulins, rhodopsin, collagen and spider silk as examples of the range of protein functions.
2.4.A.1 Denaturation of proteins by heat or by deviation of pH from the optimum.
2.4.S.1 Drawing molecular diagrams to show the formation of a peptide bond.
Modeling Protein Lab
Protein Denaturation Lab
The Macromolecules of Life
Protein Denature McGraw Hill
Amino Acid and Peptide Bond Animation
Life Cycle of a Protein
Heat Changes a Protein Structure
Amino acids and proteins from John Kyrk
Life Cycle of a Protein from Sumanas
Making polypeptides from John Kyrk
Protein Structures and Protein Folding by John Gianni