Topic 7.1 DNA Structure and Replication
Nature of science:
- Making careful observations—Rosalind Franklin’s X-ray diffraction provided crucial evidence that DNA is a double helix. (1.8)
- The structure of DNA is ideally suited to its function.
7.1 U 1 Nucleosomes help to supercoil the DNA.
7.1 U 2 DNA structure suggested a mechanism for DNA replication.
7.1 U 3 DNA polymerases can only add nucleotides to the 3’ end of a primer.
7.1 U 4 DNA replication is continuous on the leading strand and discontinuous on the lagging strand.
7.1 U 4 DNA replication is carried out by a complex system of enzymes.
7.1 U 5 Some regions of DNA do not code for proteins but have other important functions.
7.1 A 1 Rosalind Franklin’s and Maurice Wilkins’ investigation of DNA structure by X-ray diffraction.
7.1 A 2 Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing.
7.1 A 3 Tandem repeats are used in DNA profiling.
7.1 S 1 Analysis of results of the Hershey and Chase experiment providing evidence that DNA is the genetic material.
7.1 S 2 Utilization of molecular visualization software to analyse the association between protein and DNA within a nucleosome.
In the News
In the News
- Highly repetitive sequences were once classified as “junk DNA” showing a degree of confidence that it had no role. To what extent do the labels and categories used in the pursuit of knowledge affect the knowledge we obtain?
Alex Lee discusses Topic 7.1